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Surfactant effect on enhancing (S)-naproxen prodrug production from racemic naproxen by lipase

โœ Scribed by Chun-Sheng Chang; Shau-Wei Tsai

Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
409 KB
Volume
68
Category
Article
ISSN
0273-2289

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Surfactant enhancement of (S)-naproxen e
Surfactant enhancement of (S)-naproxen ester productivity from racemic naproxen by lipase in isooctane
โœ Shau-Wei Tsai; Chien-Cheng Lu; Chun-Sheng Chang ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 806 KB

In the enantioselective esterification of racemic Naproxen with trimethylsilyl methanol in isooctane by Candida cylindracea lipase, improvements in (S)-naproxen ester productivity and enzyme selectivity were demonstrated by adding bis(2-ethylhexyl) sodium sulfosuccinate (AOT) as the best surfactant.