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Surface-modified mesoporous silica with ferrocene derivatives and its ultrasound-triggered functionality

✍ Scribed by Eun Jung Kwon; Tai Gyu Lee


Book ID
104002298
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
551 KB
Volume
254
Category
Article
ISSN
0169-4332

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✦ Synopsis


Novel ferrocene derivatives designed as gatekeepers were successfully composed on the pore outlet of amino-functionalized mesoporous silica by post-synthesis grafting where the peptide bond of the amine group (-NH 2 ) of mesoporous silica was linked with the carboxylic acid group (-COOH) of both ends of the ferrocene derivatives. The materials of the amine-functionalized mesoporous silica (NH 2 -MS) and ferrocenefunctionalized mesoporous silica (Fc-CONH-MS) were characterized using X-ray diffractions (XRD), Fourier-transform infrared (FT-IR), N 2 sorption isotherms, solid-state NMR spectra, scanning electron microscopy (SEM), energy dispersive X-ray (EDX), transmission electron microscopy (TEM), and UV-vis absorption spectra. The ferrocene attached to the mesoporous silica pore outlet was cleavaged by ultrasound irradiation, which opened the closed-pore outlets, suggesting a possible application for controlled release drug carrier.