Surface Modification to Control Protein/Surface Interactions

✍ Scribed by Lin Yuan; Qian Yu; Dan Li; Hong Chen

• Book ID: 102934882
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 533 KB
• Volume: 11
• Category: Article
• ISSN: 1616-5187
• DOI: 10.1002/mabi.201000464

✦ Synopsis

Abstract

Protein/surface interactions are well known to play an important role in various biological phenomena and to determine the ultimate biofunctionality of a given material once it is in contact with a biological environment. Control over the interactions between proteins and material surfaces are not only of great theoretical interest but also of crucial importance for many biomedical applications. In this Feature Article, we summarize various successful approaches used in our laboratory and other groups for controlling protein adsorption through chemical modification of the surface and/or the introduction of specific topographic features. Some perspectives on future research in these areas are also presented.
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