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Surface modification of polyanhydride microspheres

✍ Scribed by Jinming Gao; Laura Niklason; Xiao-Mei Zhao; Robert Langer

Book ID
109388918
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
58 KB
Volume
87
Category
Article
ISSN
0022-3549

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Surface modification of PLGA microsphere
Surface modification of PLGA microspheres
✍ M. MΓΌller; J. VΓΆrΓΆs; G. CsΓΊcs; E. Walter; G. Danuser; H. P. Merkle; N. D. Spence πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 160 KB

## Abstract Microspheres made of poly(lactic‐__co__‐glycolic acid) (PLGA) are biocompatible and biodegradable, rendering them a promising tool in the context of drug delivery. However, nonspecific adsorption of plasma proteins on PLGA micro‐ and nanospheres is a main limitation of drug targeting. P