Design, Synthesis, and Biological Evalua
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Yuji Matsuya; Yuta Kobayashi; Takanori Kawaguchi; Ayana Hori; Yuka Watanabe; Ken
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Article
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2009
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John Wiley and Sons
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English
β 604 KB
## Abstract **A drug of two halves**: New artificial compounds composed of a macrosphelide core skeleton and an epothilone side chain were designed and synthesized. These compounds were more potent inducers of apoptosis than the parent naturalβtype macrosphelides.magnified image Various artificial