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Surface engineering of poly(D,L-lactic acid) by entrapment of soluble eggshell membrane protein

✍ Scribed by Jian-Wei Lu; Qiang Li; Qing-Lei Qi; Zhao-Xia Guo; Jian Yu

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
261 KB
Volume
91A
Category
Article
ISSN
1549-3296

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✦ Synopsis

Abstract

Soluble eggshell membrane protein (SEP) is used to engineer poly(D,L‐lactic acid) (PDL‐LA) membrane surface by a physical entrapment method to enhance cytocompatibility. Attenuated total reflection Fourier transform infrared spectroscopy, X‐ray photoelectron spectroscopy, and contact angle measurements are used to characterize SEP‐modified PDL‐LA membrane surface and confirm the formation of an even and stable layer of SEP on PDL‐LA membrane surface. NIH3T3 cell lines are used as model cells to evaluate cytocompatibility of the SEP‐modified PDL‐LA membrane, which is much better than that of virgin PDL‐LA membrane. The enhanced cytocompatibility facilitates potential application in tissue engineering. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009

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