Surface and cell membrane activities of leukocyte chemotactic factors
โ Scribed by WILKINSON, P. C.
- Book ID
- 109692644
- Publisher
- Nature Publishing Group
- Year
- 1974
- Tongue
- English
- Weight
- 374 KB
- Volume
- 251
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/251058a0
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๐ SIMILAR VOLUMES
Synthetic 1-O-alkyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine (PAI 0 and 1-O-alkyl-snglyceryl-3-phosphorylcholine (lyso-PAF) have previously been shown to induce chemotaxis and chemokinesis of human neutrophils. We present here data showing that these agents are inactive by themselves, but that the
Membranes prepared from rabbit neutrophils exhibit GTPase activity which can be stimulated by the chemotactic factor Met-Leu-Phe. The maximum contribution of the ATPase activities to the basal and the Met-Leu-Phe-stimulated GTPase activities are less than 20% and 9%, respectively. The basal GTPase a