Suramin inhibits duck hepatitis B virus DNA polymerase activity
β Scribed by Tsiquaye, Kwesi; Zuckerman, Arie
- Book ID
- 122277213
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 311 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0168-8278
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Replication of hepadnaviruses involves a viral DNA polymerase containing both a DNA-dependent and an RNA dependent activity. This polymerase is a potential target for chemotherapy against hepatitis B. We have used human hepatitis B virus DNA-dependent DNA polymerase from human serum and duck hepatit
We investigated effects of various DNAs on duck hepatitis B virus replication in uiuo. One-day-old ducks were infected intravenously with DHBV. Various DNAs were then iqjected intravenously, and duck hepatitis B virus levels were followed for up to 20 days after the inoculation. WhenM13 bacteriophag