Supramolecular Modification of the Periphery of Dendrimers Resulting in Rigidity and Functionality

✍ Scribed by Maurice W. P. L. Baars; Annika J. Karlsson; Victor Sorokin; Bas F. W. de Waal; E. W. Meijer

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 120 KB
• Volume: 112
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/1521-3757(20001201)112:23<4432::aid-ange4432>3.0.co;2-7

✦ Synopsis

pH measurements were made with a Corning 440 pH meter equipped with an Aldrich micro-combination electrode calibrated with standard buffer solutions of pH 4, 7, and 10.

Electrospray mass spectrometry (ESI-MS) was performed on a LCQ spectrometer (Finnigan Corporation). The sample was infused at 3 mL min À1 , and the ions were produced in an atmospheric-pressure ionization (API)/ESI ion source. The source temperature was 453 ± 473 K, and the flow rate of the drying gas was 0.9 L min À1 . A potential of 3.5 kV was applied to the probe tip, and a cone voltage of 5 ± 10 V over 200 ± 2000 Da was used. The quadrupole was scanned at 100 amu s À1 . The mass accuracy of all measurements was within 0.5 m/z units. Data acquisition and processing were performed with the Microsoft Windows NT operating system. The mass spectrum was simulated on a PC with IsoPro 3.0.

Molecular modeling was performed by using INSIGHT II (95.0, Biosym-MSI software) with the ESFF force field under the optimized pulldown in the builder module.