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Suppressor T cells in mice made unresponsive to skin allografts

✍ Scribed by KILSHAW, P. J.; BRENT, L.; PINTO, M.


Book ID
109695573
Publisher
Nature Publishing Group
Year
1975
Tongue
English
Weight
337 KB
Volume
255
Category
Article
ISSN
0028-0836

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We used in vivo and in vitro assays to determine whether suppressor cells are generated in mice rendered unresponsive to tumor-specific antigens by intravenous (i.v.) injection of non-replicating tumor cells. The results show that a single i.v. injection of 2 X lo7 irradiated P815 tumor cells result