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Suppressor of T-cell receptor signalling 1 and 2 differentially regulate endocytosis and signalling of receptor tyrosine kinases

✍ Scribed by Josipa Raguz; Sebastian Wagner; Ivan Dikic; Daniela Hoeller


Book ID
118442699
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
812 KB
Volume
581
Category
Article
ISSN
0014-5793

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Cell proliferation in response to growth factors is mediated by specific high affinity receptors. Ligand-binding by receptors of the protein tyrosine kinase family results in the stimulation of several intracellular signal transduction pathways. Key signalling enzymes are recruited to the plasma mem