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Suppressor of Cytokine Signaling-1 Is Essential for Suppressing Dendritic Cell Activation and Systemic Autoimmunity

✍ Scribed by Toshikatsu Hanada; Hiroki Yoshida; Seiya Kato; Kentaro Tanaka; Kohsuke Masutani; Jun Tsukada; Yoshio Nomura; Hiromitsu Mimata; Masato Kubo; Akihiko Yoshimura


Book ID
117723438
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
819 KB
Volume
19
Category
Article
ISSN
1074-7613

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## Abstract Neuregulin‐1 (NRG‐1) proteins promote Schwann cell survival, differentiation and proliferation during development. High levels of an NRG‐like activity are also present in some human peripheral nerve sheath tumors, suggesting that NRG‐1 isoforms may be involved in the development of thes