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Suppressive effects of transdermal clonidine administration on contact hypersensitivity reactions in guinea pigs

✍ Scribed by A.R. Goeptar; J. De Groot; M. Lang; R.G.L. van Tol; R.J. Scheper

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
451 KB
Volume
10
Category
Article
ISSN
0192-0561

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Cyclopiazonic acid (CPA) was given daily to groups of guinea pigs at doses of 0.00625, 0.0125, 0.025, 0.05, 0.1, 0.2, 0.4, 0.8, 1.6, and 1.95 mg/day for 30 days. All guinea pigs were sensitized and survivors were skin tested twenty-five days later with Mycobacterium tuberculosis. Mortalities occurre