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Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis

✍ Scribed by K. Yamamoto; W. Kitayama; A. Denda; A. Morisaki; H. Kuniyasu; M. Inoue; T. Kirita


Book ID
113607718
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
580 KB
Volume
56
Category
Article
ISSN
0940-2993

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## Abstract In this study we explored the mutation types of __p16^CDKN2A^__ exon 1 and the corresponding frequencies in experimental rat tongue carcinogenesis. Twenty barrier Sprague–Dawley (SD) rats were divided into the control (__n__ = 5) and experimental group (__n__ = 15), to which 4‐nitroquin