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Suppression of tumour necrosis factor-α by Schizonepeta tenuifolia water extract via inhibition of IκBα degradation and Jun N-terminal kinase/stress-activated protein kinase activation

✍ Scribed by Hee Kang; Sang-Woo Han; Joung-Woo Hong; Nak-Won Sohn


Book ID
118111385
Publisher
Pharmaceutical Press
Year
2010
Tongue
English
Weight
809 KB
Volume
62
Category
Article
ISSN
2042-7158

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## Abstract Tumor necrosis factor (TNF) is one of the most potent activators of nuclear transcription factor NF‐κB, c‐Jun N‐terminal protein kinase (JNK), and apoptosis in a wide variety of cells. The biological effects of TNF are mediated through sequential interactions of various cytoplasmic prot