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Suppression of tumorigenicity of a human lung carcinoma line by nontumorigenic bronchial epithelial cells in somatic cell hybrids

Book ID
122375853
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
159 KB
Volume
6
Category
Article
ISSN
0169-5002

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## Abstract A human non‐small‐cell lung carcinoma cell line, Calu‐6 (from an anaplastic carcinoma), was transfected with the Ki‐__ras__‐related anti‐oncogene K__rev__‐1. Several transfectant lines were obtained that showed a reduced tumorigenicity in nude mice with respect to the parental and contr