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Suppression of the α-isoform of class II phosphoinositide 3-kinase gene expression leads to apoptotic cell death

✍ Scribed by Shinhae Kang; Jihoon Song; Jihoon Kang; Heekyoung Kang; Daeho Lee; Youngki Lee; Deokbae Park

Book ID: 116289956
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 398 KB
Volume: 329
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2005.01.091

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## Abstract In this study the genetic control of major histocompatibility complex (MHC) class II gene expression during the transition from B cell to plasma cell has been analyzed. Class II molecules are not expressed in plasma cells because of an active suppression resulting in the abrogation of c