The dasC mutation, an extragenic suppressor of dnaA46, was mapped by P1 transduction near the rep, trxA, rho region of the Escherichia coli chromosome. The dasC mutation could not be separated from trxA by P1 transduction indicating that dasC and trxA are allelic. Multicopy plasmids containing an in
Suppression of the lexC (ssbA) mutation of Escherichia coli by a mutant of bacteriophage P1
โ Scribed by Johnson, Ben F.
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 569 KB
- Volume
- 186
- Category
- Article
- ISSN
- 0026-8925
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โฆ Synopsis
A new mutant of bacteriophage P1 designated lxc that suppresses the phenotype of lexC and ssbA mutants of Escheriehia eoli was isolated and characterized. The properties of lexC mutants suppressed by the lxc mutation include temperature sensitive growth at 42 ยฐ C, sensitivity to ultraviolet light and alkylating agents, and a nonmutagenic response following exposure to ultraviolet irradiation. A bac mutant of bacteriophage P1 that suppresses the temperature sensitivity of dnaB mutants does not affect the phenotype of lexC or ssbA mutants. Neither the lxc or bac mutations affect the ultraviolet light sensitivity of strains with the mutations uvrA155, lexAl02, or recA56.
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