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Suppression of the immune response to an adenovirus vector and enhancement of intratumoral transgene expression by low-dose etoposide

โœ Scribed by Bouvet, M; Fang, B; Ekmekcioglu, S; Ji, L; Bucana, C D; Hamada, K; Grimm, E A; Roth, J A


Book ID
110038128
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
740 KB
Volume
5
Category
Article
ISSN
0969-7128

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## Abstract ## Background Transfecting cells with plasmid DNA encoding the protein Bax causes programmed cell death (apoptosis) and results in the formation of cell fragments (apoptotic bodies). It has been known for some time that when dendritic cells phagocytose apoptotic bodies derived from tum