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Suppression of the enzymes of glutamate metabolism in cortical synaptosomes in methionine sulfoximine toxicity

✍ Scribed by G.Y.C.V. Subbalakshmi; Ch.R.K. Murthy


Book ID
118942541
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
420 KB
Volume
35
Category
Article
ISSN
0024-3205

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## Abstract D‐methionine was administered intraperitoneally to rats in tracer (2–2.5 ΞΌmoles/kg) and large doses (4.7 mmoles/kg) and the brain levels of total (D + L) methionine, as well as of cysteine (+cystine) and glutathione were determined. The effect of co‐administering the convulsant agent, L