Suppression of TGF-β signaling system a myofibroblast differentiation in human corne and limbal fibroblasts by amniotic membra matrix

Suppression of transforming growth facto

Suppression of transforming growth factor-beta isoforms, TGF-β receptor type II, and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix

✍ Scheffer C.G. Tseng; De-Quan Li; Xiang Ma 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 326 KB 👁 1 views

Down-regulation of the transforming growth factor-beta (TGF-␤) signaling system is a strategy for preventing scarring during wound healing. Human corneal and limbal fibroblasts were cultured on the stromal matrix side of preserved human amniotic membrane. The levels of TGF-␤1, ␤2, and ␤3 and TGF-␤ t