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Suppression of T-cell responses by tumor metabolites

✍ Scribed by Katrin Singer; Eva Gottfried; Marina Kreutz; Andreas Mackensen


Book ID
105967869
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
301 KB
Volume
60
Category
Article
ISSN
0340-7004

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## Abstract T‐box‐containing protein expressed in T cells (T‐bet) is a master transcription factor for the development of interferon (IFN) γ‐producing T helper 1 (Th1) cells and also functions in other immune cells including natural killer (NK), cytotoxic T lymphocytes and dendritic cells. T‐bet‐de