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SUPPRESSION OF PRIMARY TUMOR GROWTH AND THE PROGRESSION TO METASTASIS WITH p53 ADENOVIRUS IN HUMAN PROSTATE CANCER

โœ Scribed by EASTHAM, JAMES A.; GRAFTON, WARREN; MARTIN, CINDY M.; WILLIAMS, B. JILL


Book ID
121353944
Publisher
Lippincott Williams and Wilkins
Year
2000
Tongue
English
Weight
883 KB
Volume
164
Category
Article
ISSN
0022-5347

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We have previously described potent growth-inhibitory effect of a recombinant adenovirus expressing wild type p53 (AdWTp53) in metastatic prostate cancer cells via activation of cellular p53 pathways. We have extended these observations to analyze the effects of AdWTp53 on primary cultures of radica