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Suppression of PPN/MG61 attenuates Wnt/β-catenin signaling pathway and induces apoptosis in human lung cancer

✍ Scribed by Chen, Z; Li, J; Li, Q S; Fan, J Q; Dong, X M; Xu, J P; Wang, X M; Yang, G W; Yan, P; Wen, G Z

Book ID
110072983
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
271 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract Constitutive activation of the Wnt pathway as a result of __APC__, __AXIN1__ or __CTNNB1__ mutations has been found in most colorectal cancers. For a long time, this aberrant Wnt activation has been thought to be independent of upstream signals. However, recent studies indicate that ups