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Suppression of parathyroid hormone‐related protein messenger RNA expression by medroxyprogesterone acetate in breast cancer tissues

✍ Scribed by Takuji Sugimoto; Eiichi Shiba; Taro Watanabe; Shin‐ichiro Takai

Book ID
110233556
Publisher
Springer US
Year
1999
Tongue
English
Weight
178 KB
Volume
56
Category
Article
ISSN
0167-6806

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Parathyroid hormone-related protein (PTHrP) is the cause of humoral hypercalcaemia of malignancy and interacts with parathyroid hormone (PTH) receptors. Breast cancer cells produce PTHrP in vitro and in vivo. The breast cancer cell line MCF-7, which products PTHrP and expresses PTHrP receptors, prol