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Suppression of osteoclastogenesis in rheumatoid arthritis by induction of apoptosis in activated CD4+ T cells

✍ Scribed by Yukie Ogawa; Masahiko Ohtsuki; Miwa Uzuki; Takashi Sawai; Yoshiko Onozawa; Junichi Nakayama; Akiko Yonemura; Tomoatsu Kimura; Hiroaki Matsuno


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
276 KB
Volume
48
Category
Article
ISSN
0004-3591

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## Abstract ## Objective We previously demonstrated that CD4+,CD25+ regulatory T (Treg) cells are present in increased numbers in the synovial fluid (SF) of rheumatoid arthritis (RA) patients and display enhanced suppressive activity as compared with their peripheral blood (PB) counterparts. Despi