𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells

✍ Scribed by Xu, Changjiang; Shen, Guoxiang; Chen, Chi; Gélinas, Céline; Kong, Ah-Ng Tony

Book ID
110069705
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
348 KB
Volume
24
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Blockage of NF-κB by IKKβ- or RelA-siRNA
Blockage of NF-κB by IKKβ- or RelA-siRNA rather than the NF-κB super-suppressor IκBα mutant potentiates adriamycin-induced cytotoxicity in lung cancer cells
✍ Wenshu Chen; Xia Wang; Lang Bai; Xiaomin Liang; Jianguo Zhuang; Yong Lin 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 260 KB

## Abstract Ambiguous roles of genotoxic anticancer therapeutic‐induced NF‐κB activation in regulating gene expression (activation or suppression) and apoptosis (anti‐ or pro‐apoptosis) have recently been suggested. In order to clarify this controversy and determine the usefulness of NF‐κB blockage

Betulinic acid suppresses constitutive a
Betulinic acid suppresses constitutive and TNFα-induced NF-κB activation and induces apoptosis in human prostate carcinoma PC-3 cells
✍ Thangaiyan Rabi; Sanjeev Shukla; Sanjay Gupta 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 251 KB

## Abstract Development of chemoresistance in androgen‐refractory prostate cancer cells is partly due to constitutive activation of Rel/NF‐κB transcription factors that regulate several cell survival and anti‐apoptotic genes. In this study we examined whether betulinic acid (BetA), a pentacyclic tr

Suppression of TNFα-mediated NFκb activi
Suppression of TNFα-mediated NFκb activity by myricetin and other flavonoids through downregulating the activity of IKK in ECV304 cells
✍ Shu-Huei Tsai; Yu-Chih Liang; Shoei-Yn Lin-Shiau; Jen-Kun Lin 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB 👁 1 views

Flavonoids are a group of naturally-occurring phenolic compounds in the plant kingdom, and many flavonoids are found with vascular protective properties. Nevertheless how the protective response is exerted by flavonoids is not well characterized. In view of the nuclear factor-B (NFB) may play a cent