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Suppression of myoclonus in SCA2 by piracetam

✍ Scribed by Anna De Rosa; Pasquale Striano; Fabrizio Barbieri; Arturo De Falco; Carlo Rinaldi; Tecla Tucci; Salvatore Striano; Alessandro Filla; Giuseppe De Michele


Book ID
102507691
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
52 KB
Volume
21
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

We report on a 30‐year‐old patient with advanced cerebellar degeneration due to SCA2. He presented with severe myoclonus, which was resistant to conventional therapy and dramatically improved after administration of 12–18 gm/die piracetam. Piracetam may be considered in the treatment of refractory myoclonus in spinocerebellar degenerations. Β© 2005 Movement Disorder Society


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## Abstract Sixty patients with disabling myoclonus excluding mainly spinal myoclonus were treated by piracetam as an open‐labeled study, and myoclonus score, neurological symptoms, functional disbility, and intensity of myoclonus were scored before and after treatment, including a blinded video in