## Abstract Twentyβone patients with disabling spontaneous, reflex, or action myoclonus due to various causes, who had shown apparent clinical improvement on introduction of piracetam, entered a placeboβcontrolled doubleβblind crossover trial of piracetam (2.4β 16.8 g daily). All but one patient ha
Suppression of myoclonus in SCA2 by piracetam
β Scribed by Anna De Rosa; Pasquale Striano; Fabrizio Barbieri; Arturo De Falco; Carlo Rinaldi; Tecla Tucci; Salvatore Striano; Alessandro Filla; Giuseppe De Michele
- Book ID
- 102507691
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 52 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
We report on a 30βyearβold patient with advanced cerebellar degeneration due to SCA2. He presented with severe myoclonus, which was resistant to conventional therapy and dramatically improved after administration of 12β18 gm/die piracetam. Piracetam may be considered in the treatment of refractory myoclonus in spinocerebellar degenerations. Β© 2005 Movement Disorder Society
π SIMILAR VOLUMES
## Abstract Sixty patients with disabling myoclonus excluding mainly spinal myoclonus were treated by piracetam as an openβlabeled study, and myoclonus score, neurological symptoms, functional disbility, and intensity of myoclonus were scored before and after treatment, including a blinded video in