Suppression of multidrug resistance via inhibition of heat shock factor by quercetin in MDR cells
β Scribed by Kim, Sun-Hee; Yeo, Gae-Sun; Lim, Young-Sun; Kang, Chi-Dug; Kim, Cheol-Min; Chung, Byung-Seon
- Book ID
- 121268017
- Publisher
- Korean Society of Medical Biochemistry and Molecular Biology
- Year
- 1998
- Tongue
- English
- Weight
- 192 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1226-3613
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Combination of heat and various anticancer drugs can exert a synergistic antitumor effect in vitro and in vivo, though the mechanism is not clear. We have previously shown that endogenous tumor necrosis factor (enTNF) acts as an intracellular resistance factor to inhibit the cytotoxic effect of heat