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Suppression of MMP activity in bovine cartilage explants cultures has little if any effect on the release of aggrecanase-derived aggrecan fragments

✍ Scribed by Bijue Wang; Pingping Chen; Anne-Christine Bay Jensen; Morten A Karsdal; Suzi H Madsen; Bodil-Cecilie Sondergaard; Qinlong Zheng; Per Qvist

Book ID: 115024718
Publisher: BioMed Central
Year: 2009
Tongue: English
Weight: 441 KB
Volume: 2
Category: Article
ISSN: 1756-0500
DOI: 10.1186/1756-0500-2-259

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131 SUPPRESSION OF MMP ACTIVITY IN BOVIN

131 SUPPRESSION OF MMP ACTIVITY IN BOVINE CARTILAGE EXPLANTS CULTURES HAS LITTLE IF ANY EFFECT ON THE RELEASE OF AGGRECAN FRAGMENTS CARRYING AGGRECANASE-DERIVED NEO-EPITOPES, WHEREAS CORRESPONDING MMP-DERIVED AGGRECAN AND COLLAGEN FRAGMENTS ARE COMPLETELY ABOLISHED FROM THE SUPERNATANT

✍ B. Wang; P. Chen; A.C. Bay-Jensen; M. Karsdal; S.H. Madsen; B.C. Sondergaard; Q. 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 174 KB