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Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation

✍ Scribed by Woan-Ruoh Lee; Chi-Li Chung; Che-Jen Hsiao; Yung-Chen Chou; Po-Jen Hsueh; Po-Chih Yang; Jing-Shiun Jan; Yu-Wen Cheng; George Hsiao

Book ID: 113848989
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 669 KB
Volume: 19
Category: Article
ISSN: 0944-7113
DOI: 10.1016/j.phymed.2011.11.012

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## Abstract Matrix metalloproteinase‐9 (MMP‐9) plays a critical role in tumor invasion and metastasis. Here, we investigate the effect of fibroblast growth factor‐1 (FGF‐1) on the expression of MMP‐9 in ENU1564, an ethyl‐__N__‐nitrosourea‐induced rat mammary adenocarcinoma cell line. We observed th