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Suppression of insulin receptor activation by overexpression of the protein-tyrosine phosphatase LAR in hepatoma cells

✍ Scribed by Pei-Ming Li; Wei-Ren Zhang; Barry J. Goldstein

Book ID: 114283993
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 710 KB
Volume: 8
Category: Article
ISSN: 0898-6568
DOI: 10.1016/s0898-6568(96)00101-5

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Various molecular forms of chromium have been implicated in the regulation of glucose metabolism, and chromium deficiency can be associated with insulin resistance and impaired glucose tolerance. Protein-tyrosine phosphatases (PTPases), which negatively regulate signaling through the insulin recepto