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Suppression of inflammatory responses of endothelial cells by shear stress: Role of integrin signalling

✍ Scribed by N.-T. Luu; K. Glen; S. Egginton; G.E. Rainger; G.B. Nash

Book ID
118423242
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
50 KB
Volume
213
Category
Article
ISSN
0021-9150

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## Abstract Exposure of endothelial cells (EC) to shear stress reduces their response to tumour necrosis factor‐α (TNF). We tested how shear‐conditioned EC responded to reduction in flow, either by spontaneously binding leukocytes, or by increasing sensitivity to TNF. Human umbilical vein EC were e