Suppression of immune responses to β-lactoglobulin in mice by the oral administration of peptides representing dominant T cell epitopes

The mouse chorionic gonadotropin β-subun

The mouse chorionic gonadotropin β-subunit-like (muCGβl) molecule produced by tumor cells elicits the switch of T-cell immunity response from TH2 to TH1 in mice immunized with DNA vaccine based on rhesus monkey homologous CGβ (rmCGβ)

✍ Shu-Qun Shi; Jing-Pian Peng; Li Xu; Ying Yang; Yun Chen 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB 👁 1 views

## Abstract ## Background CGβ is expressed not only in placenta, but also in a wide range of tumors. To study DNA vaccine based on xenogeneic CGβ for cancer immuno‐therapy, we investigated whether rhesus monkey CGβ (rmCGβ) DNA vaccine could induce protective T‐cell responses and humoral responses