𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Suppression of IL-8 gene expression by radicicol is mediated through the inhibition of ERK1/2 and p38 signaling and negative regulation of NF-κB and AP-1

✍ Scribed by Yong Ju Na; Young Jin Jeon; Jae-Hong Suh; Jong Soon Kang; Kyu-Hwan Yang; Hwan-Mook Kim

Book ID
117797909
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
262 KB
Volume
1
Category
Article
ISSN
1567-5769

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Transcriptional regulation of IL-8 by ir
Transcriptional regulation of IL-8 by iron chelator in human epithelial cells is independent from NF-κB but involves ERK1/2- and p38 kinase-dependent activation of AP-1
✍ Eun-Young Choi; Zee-Yong Park; Eun-Ju Choi; Hyun-Mee Oh; SungGa Lee; Suck-Chei C 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 402 KB 👁 2 views

## Abstract We have shown that the bacterial iron chelator, deferoxamine (DFO), triggers inflammatory signals including the production of CXC chemokine IL‐8, in human intestinal epithelial cells (IECs) by activating the ERK1/2 and p38 kinase pathways. In this study we investigated the mechanisms in

Blockade of IL-15 activity inhibits micr
Blockade of IL-15 activity inhibits microglial activation through the NFκB, p38, and ERK1/2 pathways, reducing cytokine and chemokine release
✍ Diego Gomez-Nicola; Beatriz Valle-Argos; Manuel Nieto-Sampedro 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 557 KB

## Abstract Reactive glia formation is one of the hallmarks of damage to the CNS, but little information exists on the signals that direct its activation. Microglial cells are the main regulators of both innate and adaptative immune responses in the CNS. The proinflammatory cytokine IL‐15 is involv