Inhibition of cell growth of human hepat
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Toshihiko Nagase; Sumio Kawata; Shinji Tamura; Yukihiko Matsuda; Yoshiaki Inui;
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Article
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1996
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John Wiley and Sons
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French
โ 776 KB
So far, treatment with anti-cancer agents has failed to achieve satisfactory results in hepatocellular carcinoma. In the process of hepatocarcinogenesis, ras has been shown to play a role. ras requires a farnesyl moiety for activation. It has been found that UCF I -C (manumycin). an antibiotic, inhi