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Suppression of hepatocellular carcinoma growth in mice via leptin, is associated with inhibition of tumor cell growth and natural killer cell activation

✍ Scribed by Eran Elinav; Asad Abd-Elnabi; Orit Pappo; Itamar Bernstein; Athalia Klein; Dean Engelhardt; Elazar Rabbani; Yaron Ilan


Book ID
116650885
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
349 KB
Volume
44
Category
Article
ISSN
0168-8278

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## Abstract The Wnt/β‐catenin signaling pathway regulates various aspects of development and plays important role in human carcinogenesis. Nemo‐like kinase (NLK), which is mediator of Wnt/β‐catenin signaling pathway, phosphorylates T‐cell factor/lymphoid enhancer factor (TCF/LEF) factor and inhibit