In vitro HBV infection and neutralization were assayed using an anti-preS1 murine monoclonal antibody (1B3) and anti-preS2 (H69K) and anti-S (CS131A) murine-human chimeric antibodies. The 1B3 (IgG1) and H69K (IgG1) was constructed previously and the CS131A was constructed for this study by expressin
Suppression of Hepatitis B Virus Surface Antigen Secretion by Traditional Plant Medicines
β Scribed by Wakana Goto; Ines Tomoco Kusumoto; Shigetoshi Kadota; Tsuneo Namba; Mashahiko Kurokawa; Kimiyasu Shiraki
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 402 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
β¦ Synopsis
Forty
-three extracts of herbal medicines were tested for suppressing the secretion of hepatitis B virus (HBV) surface antigen (HBsAg) in v h o . Fourteen extracts were found to have appreciable effects in the experimental system using the PLC/PRF/5 cell line. Of them, the extracts of Rheum palmdurn (rhizome), Poligonurn cuspidaturn (mot), P a m japonicurn (root) and TeminuZia atjuna (bark) strongly suppressed the secretion of HBsAg. The active constituents of these extracts absorbed through the gastrointestinal tract of guinea-pigs suppressed the secretion of HBsAg in the PLWRF/5 cell culture.
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