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Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein and its fragments

✍ Scribed by Paul J. Higgins; Howard L. Weiner

Book ID: 119106981
Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 62 KB
Volume: 16
Category: Article
ISSN: 0165-5728
DOI: 10.1016/0165-5728(87)90246-3

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## Abstract Self antigens bind to MHC class II molecules __in vivo__. The capacity of class II molecules to bind native self antigen, namely antigen that has not been processed through an endososomal pathway, could increase susceptibility to autoimmune diseases if recognized by autoreactive T lymph