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Suppression of eosinophilic airway inflammation by treatment with α-galactosylceramide

✍ Scribed by Yuko Morishima; Yukio Ishii; Toru Kimura; Akira Shibuya; Kazuko Shibuya; Ahmed E. Hegab; Takashi Iizuka; Takumi Kiwamoto; Yosuke Matsuno; Tohru Sakamoto; Akihiro Nomura; Masaru Taniguchi; Kiyohisa Sekizawa

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
496 KB
Volume
35
Category
Article
ISSN
0014-2980

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Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of α-galactosylceramide
✍ Asako Chiba; Shinji Oki; Katsuichi Miyamoto; Hiroshi Hashimoto; Takashi Yamamura 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 2 views

## Abstract ## Objective OCH, a synthetic analog of α‐galactosylceramide with a truncated sphingosine chain, stimulates natural killer T (NKT) cells to produce predominantly Th2 cytokines. Thus, OCH may be a potential agent for the treatment of Th1‐mediated autoimmune diseases. This study was desi