In women, calcium excretion in the urine rises after menopause and falls with estrogen replacement therapy. The amount of calcium lost in the urine following estrogen therapy is less than should occur based on changes in serum calcium and the amount of calcium filtered by the kidney. This suggests t
β¦ LIBER β¦
Suppression of calbindin D28K in estrogen-induced hamster renal tumors
β Scribed by Hari K. Bhat; Irina Epelboym
- Book ID
- 116697456
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 347 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0960-0760
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## Abstract Cyclosporine A (CsA) is known to have direct toxicity to renal tubular cells. Its toxicity may be mediated by intracellular calcium because CsA increases intracellular calcium concentration and enhances the activities of calciumβdependent calpains and caspases. CalbindinβD~28k~, a cytos