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Suppression of B-memory cell function by polyclonal lymphocyte activators

โœ Scribed by Yokochi, Takashi; Nakashima, Izumi; Fujii, Yasuaki; Kato, Nobuo

Book ID
121780151
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
706 KB
Volume
158
Category
Article
ISSN
0171-2985

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Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells
โœ Bernasconi, N. L. ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› American Association for the Advancement of Scienc ๐ŸŒ English โš– 260 KB

Production of antibodies can last for a lifetime, through mechanisms that remain poorly understood. Here, we show that human memory B lymphocytes proliferate and differentiate into plasma cells in response to polyclonal stimuli, such as bystander T cell help and CpG DNA. Furthermore, plasma cells se