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Suppression of allergic airway disease using mycobacterial lipoglycans

✍ Scribed by Sayers, Ian; Severn, Wayne; Scanga, Connie B; Hudson, Jenny; Le Gros, Graham; Harper, Jacquie L

Book ID
119274466
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
268 KB
Volume
114
Category
Article
ISSN
1097-6825

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## Abstract Hypoxia‐inducible factor‐1Ξ± (HIF‐1Ξ±) plays a critical role in immune and inflammatory responses. One of the HIF‐1Ξ± target genes is vascular endothelial growth factor (VEGF), which is a potent stimulator of inflammation, airway remodeling, and physiologic dysregulation in allergic airway