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Suppression of 12-O-Tetradecanoylphorbol-13-Acetate-Induced MCF-7 Breast Adenocarcinoma Cells Invasion/Migration by α-Tomatine Through Activating PKCα/ERK/NF-κB-Dependent MMP-2/MMP-9 Expressions

✍ Scribed by Min-Der Shi, Yuan-Wei Shih, Ya-Shan Lee…

Book ID
120897758
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
798 KB
Volume
66
Category
Article
ISSN
1085-9195

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✍ Cheng-Wei Lin; Shing-Chuan Shen; Chih-Chiang Chien; Liang-Yo Yang; Lin-Ting Shia 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 588 KB

## Abstract An increase in __MMP‐9__ gene expression and enzyme activity with stimulating the migration of GBM8401 glioma cells via wound healing assay by 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA) was detected in glioblastoma cells GBM8401. TPA‐induced translocation of protein kinase C (PKC)α