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Suppression by heparin of smooth muscle cell proliferation in injured arteries

✍ Scribed by CLOWES, ALERANDER W.; KARNOWSKY, MORRIS J.


Book ID
109703875
Publisher
Nature Publishing Group
Year
1977
Tongue
English
Weight
355 KB
Volume
265
Category
Article
ISSN
0028-0836

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Vascular smooth muscle cell (VSMC) hyperplasia plays a central role in chronic and acute vascular pathology including arteriosclerosis and restenosis following vascular surgery. The glycosaminoglycans of the heparan sulfate class, including heparin, inhibit VSMC proliferation in animals and in cultu