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Suppressed acute phase response to LPS-induced hepatic injury in Smad3-deficient mice

โœ Scribed by Jia-Hui Li; Kai-Yang Lv; Heng-Yu Li; Zhao-Fan Xia


Book ID
116757219
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
385 KB
Volume
46
Category
Article
ISSN
0161-5890

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## Abstract Acute apoptotic response to genotoxic carcinogens (AARGC) might be important for controlling the consequences of mutational load in the colon. It has been shown to occur in parallel with activation of DNA repair mechanisms. Inadequate AARGC might allow development of mutated clones with