𝔖 Bobbio Scriptorium
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Supplement 3: Environmental Mutagens || Distinction of Mutagenic Carcinogens from a Mutagenic Noncarcinogen in the Big Blue Transgenic Mouse

✍ Scribed by Michael L. Cunningham, Jeffrey J. Hayward, Barbara S. Shane and Kenneth R. Tindall


Book ID
124301055
Publisher
Environmental Health Information Service
Year
1996
Tongue
English
Weight
973 KB
Volume
104
Category
Article
ISSN
0091-6765

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System Issues: Mutagenic response of the
✍ Thomas R. Skopek; Kristy L. Kort; Deborah R. Marino; Lakshmi V. Mittal; Diane R. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 807 KB

Big Blue@ (BB) and generic B6C3F1 mice were given one to three i.p. injections of 50 mg/kg benzo[a]pyrene (B[a]P) in DMSO every other day to achieve cumulative doses of 50 to 150 mg/kg. Three weeks after treatment, the mutation frequency at the endogenous hprt gene and lac/ transgene was measured in