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Superunstable alleles at the cut locus in Drosophila melanogaster

โœ Scribed by Gerasimova, T. I.

Publisher
Springer
Year
1983
Tongue
English
Weight
453 KB
Volume
190
Category
Article
ISSN
0026-8925

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โœฆ Synopsis

This is a detailed study of the reversions of the ctMR2 allele putatively carrying รก mobile element (MR-transposon) in the cut locus. Stable, unstable and superunstable revertants have been identified. Besides, a series of multiple unstable visible and lethal ct mutations derived from the ctMR2 allele have been obtained. They are shown to include supermutable alleles. The results suggest that the MR-transposon is connected with at least three functions: excision; change of orientation; and change of position within the cut locus, these functions being disturbed in different ways in different unstable ct+ and ct alleles. In some cases the mutant transitions are somehow strongly stimulated leading to superinstability, reaching the rate of 0.5.

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