Rapid dissolution of high-potency danazo
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Xiaoxia Chen; Jason M. Vaughn; Miguel J. Yacaman; Robert O. Williams III; Keith
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Article
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2004
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John Wiley and Sons
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English
โ 188 KB
High-potency danazol particles with high dissolution rates were produced by evaporative precipitation into aqueous solution (EPAS). Aqueous suspensions formed by EPAS were centrifuged to remove the nonadsorbed surfactant. The resulting surfactant-coated drug particles had extremely high drug-to-surf