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Superparamagnetic silica nanoparticles with immobilized metal affinity ligands for protein adsorption

✍ Scribed by Zhiya Ma; Yueping Guan; Huizhou Liu


Book ID
113724060
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
249 KB
Volume
301
Category
Article
ISSN
0304-8853

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## Abstract A new chelating compound has been developed for use in the immobilized metal affinity chromatographic (IMAC) separation of proteins. The bidentate ligand, α‐amino phenylalanine tetrazole, **4**, was synthesized __via__ a five‐step synthesis from __N__‐fluorenylmethoxycarbonyl phenylalan